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Blood thickens, vessels stiffen.
With age, fibrin builds up in the blood and artery walls lose their spring. Two problems, one system.
90-Day Protocol — Save $20
10,000+ SOLD MADE IN USA 3rd-party tested
Support the elasticity & strength of your arteries
Arterial health changes quietly with age. Tygrix Nattokinase 7-in-1 combines researched ingredients to support healthy blood flow, flexible vessels and normal heart function.*
- Silent danger: Clogged arteries restricting blood flow 24/7
- Arterial damage: Reduced oxygen flow to vital organs
- Cardiovascular risk: Increased chance of heart attack or stroke
120-Day Money Back Guarantee · Save $20 on the 90-Day Protocol Ships from US
120-Day Money Back Guarantee12,000 FU Per Serving7 Actives, Every Dose on the LabelNo Proprietary BlendsEnteric-Coated CapsulesVegetarian Capsules3rd Party TestedMade in USA · GMP facilityFree US Shipping
“I've been using this to support my heart and remove arterial plaque and they've been really helpful”
Harrold Aitchison — Former football manager
Join 10,000+ Men Supporting Heart Health Naturally
What it does
Nattokinase 7-in-1
Circulation Complex
Seven fully dosed actives in two capsules. Three enzymes for the blood, two botanicals for the vessel, two nutrients for the heart.
- Supports cardiovascular health*12,000 FU of nattokinase, more than the 10,800 FU dose used in a 12-month study of 1,062 people.
- Supports normal heart function*CoQ10 100 mg fuels the energy your heart muscle runs on.
- Supports strong, healthy blood vessels*pine bark extract 100 mg supports healthy vessel lining function.
- Supports elastic, flexible artery walls*Vitamin K2 MK-7 200 mcg helps route calcium to your bones instead of your arteries.
- Supports healthy blood pressure already within normal range*aged garlic extract standardized to 1.2 mg S-allylcysteine, the same SAC amount used in a 12-week double-blind trial.
- Supports healthy cholesterol levels already within normal range*nattokinase plus aged garlic extract.
- Supports healthy blood flow and vessel dilation*pine bark and CoQ10 have both been studied for flow-mediated dilation.
Nattokinase 12,000 FU — natto enzymeSerrapeptase 240,000 SPU — proteolytic enzymeLumbrokinase 40 mg — third enzymeAged Garlic Extract 480 mgPine Bark Extract 100 mgCoQ10 100 mgVitamin K2 MK-7 200 mcg
*These statements have not been evaluated by the Food and Drug Administration.
How it works
Here's how Nattokinase 7-in-1 works
2
Three enzymes work on the blood.
Nattokinase, serrapeptase and lumbrokinase support healthy fibrin balance and your body's own natural fibrinolytic activity, so blood moves easily.*
3
Four nutrients work on the vessel and heart.
Aged garlic, pine bark and K2 support flexible, healthy arteries. CoQ10 fuels the heart that pushes blood through them.*
Every single batch tested
We test every batch.
Quality you can check.
We test every single production batch through an independent ISO 17025 accredited laboratory before it ships.
Third-party testedBatch N1889
Every batch goes to an independent laboratory — tested for what’s in it, and for what shouldn’t be.
Dosage
Confirms each capsule contains the amount stated on the label
Identity
Confirms the ingredient is genuinely what it claims to be
Heavy Metals
Screened for lead, arsenic, cadmium and mercury
Microbiological
Screened for bacterial, yeast and mould contamination
Not all nattokinase is created equal
Independent laboratory potency results supplied by Tygrix. Percentages show potency relative to the label claim.
Tygrix
163%
Tygrix batch N1889 · 163% of label claim.
Natural Foundation
Horbaach
Double Wood
Luma Nutrition
Bulk Supplements
Noverly
Black Forest Supplements
“90% of Amazon brands tested were underdosed.”
Testing summary and figures supplied by Tygrix. The summary refers to Tygrix’s reported testing pool, not a calculation from the seven competitor rows above. Laboratory reports are not displayed on this page.
3rd Party Tested — Eurofins 163% Potency GMP Facility · Made in USA
12,000FU
Tygrix per serving
10,800 FU
the daily dose used in the 12-month, 1,062-person study
3,600 FU
found ineffective in the same study
Your 12-month journey
How your circulation support builds over time
This is why we recommend starting with the 90-Day Flow Protocol and staying consistent. The largest nattokinase study followed people for a full 12 months.
Month 0 — Starting point
The stairs feel longer than they used to. Thicker blood and stiffer vessels built up over decades, not weeks.
Month 4 — Early progress
Three enzymes have been at work every single day. Consistency is where daily support starts to add up.*
Month 8 — Building
The vessel side has had time to catch up. K2, garlic and pine bark have been supporting flexible arteries for months.*
Month 12 — Full course
A full year. The same length of time researchers used in the 1,062-person study.
Timeline based on the 12-month study (10,800 FU/day). doi.org/10.3389/fcvm.2022.964977 Individual results vary.
Choose Your Plan
Nattokinase 7-in-1 Circulation Complex — 12,000 FU
30 Day Supply
Just $1.50 per day
Most Popular — 90-Day Flow Protocol
90 Day Supply
Only $1.28 per day
3 bottles · 90-day supply
Free with your order
- Free The 90-Day Circulation Log
$27 - Free US Shipping
- 3 bottles, the full protocol
- Free US shipping
- 120-day guarantee
Best Value — Lowest Price Per Day
Full Reset
Only $1.11 per day
6 bottles · 180-day supply
Free with your order
- Free The 90-Day Circulation Log
$27 - Free The Morning Flow Routine
$27 - Free US Shipping
- Six months at the lowest price per day
- Both free gifts included
- 120-day money-back guarantee
The 90-Day Circulation Log — worth $27, free with 3 or 6 bottles. The Morning Flow Routine — worth $27, free with 6 bottles.
120-day guaranteeShips from US3rd-party testedBacked by science
Real customers, real results
Reviews from our product page · Imported via Judge.me
★★★★☆
Nattokinase
Feels refreshed and with a bit of energy after taking these supplements,it's a boost especially while working out
Raul TImported review
★★★★★
Good product….
Geary WilliamsImported review
★★★★☆
Feels like it is working
Can feel a change, hopefully it's worth it.
Henry Morgan SrImported review
★★★★★
Great stuff
Douglas HoltImported review
★★★★★
The product is easy to take and seems to be working well, time will reveal more.
Adam BaileyImported review
★★★★★
Excellent Product
Excellent Product
Joseph JacksonImported review
★★★★★
it appears to be working
TIMOTHY VICKERYImported review
★★★★★
Simply the best
JEFFREY SWAGERImported review
Scientific research
Backed by published clinical studies
12,000 FU
more than the 10,800 FU per day used in a published 12-month study of 1,062 people.
frontiersin.org/journals/cardiovascular-medicineFAQs
Questions About Nattokinase 7-in-1?
Everything you need to know: ingredients, dosage, safety and shipping.
About the Product
A two-capsule daily formula with seven fully dosed actives: Nattokinase 12,000 FU, Serrapeptase 240,000 SPU, Lumbrokinase 40 mg, Aged Garlic Extract 480 mg (1.2 mg SAC), Pine Bark Extract 100 mg, CoQ10 100 mg and Vitamin K2 MK-7 200 mcg. Every dose is on the label. No proprietary blends.
An enzyme from natto, a traditional Japanese fermented soybean food eaten for centuries and widely researched for cardiovascular support.
They are two more enzymes that work alongside nattokinase to support healthy fibrin balance and easy blood flow.*
K2 MK-7 activates a protein that helps keep calcium out of artery walls and direct it to your bones.* In the 1,062-person nattokinase study, pairing nattokinase with K2 produced a synergistic effect. Important: if you take warfarin or another vitamin K antagonist, do not take this product without your doctor's approval, because vitamin K changes how those medicines work.
How to Take It
2 capsules daily with a full glass of water.
Any time of day. Pick one time and stay consistent. The capsules are enteric coated, so they're built to pass the stomach intact.
Give it at least 3 months. The largest nattokinase study ran for 12 months.
Check with your doctor first, especially if you take fish oil, vitamin E, ginkgo or anything else that affects blood flow.
Quality & Safety
If you take blood thinners (including warfarin), aspirin or any prescription medication, have a medical condition, or have surgery scheduled, talk to your doctor before use.
The capsules are vegetarian. PLACEHOLDER[CONFIRM full vegetarian/vegan status with supplier.]
Made in the USA in a GMP facility. Every production batch is third-party tested by Eurofins.
Contains soy. PLACEHOLDER[Confirm: free from gluten, dairy, nuts, artificial colours or preservatives.]
Shipping & Guarantee
PLACEHOLDER[Dispatch time. US 3–7 business days.]
Free shipping on all US orders.
120 days, money back. Not happy, email us.
The 90-Day Flow Protocol. Consistency matters, and three months is the minimum we'd judge it on.
Still have questions? support@tygrixsupplements.store
Start today
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Get My 90-Day Flow Protocol*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
90-Day Protocol — Save $20 · Free US shipping
Get My 90-Day Flow ProtocolSee the scientific studies
10,800 FU/day · Nattokinase
12-month clinical study
Researchers tracked artery wall thickness and blood lipids. The 10,800 FU dose produced significant improvements; 3,600 FU per day did not. Pairing nattokinase with vitamin K2 produced a synergistic effect.
Tygrix: 12,000 FU + K2.
doi.org/10.3389/fcvm.2022.964977 ↗180 mcg/day · Vitamin K2 MK-7
3-year double-blind randomized trial
Arterial stiffness improved vs placebo.
Tygrix: 200 mcg.
doi.org/10.1160/TH14-08-0675 ↗1.2 mg SAC/day · Aged garlic extract
12-week double-blind randomized trial
Average systolic readings were 5 mmHg lower than placebo.
Tygrix: 1.2 mg SAC.
doi.org/10.2147/IBPC.S93335 ↗200 mg/day · Pine bark extract
8-week double-blind crossover trial
Flow-mediated dilation improved from 5.3% to 7.0%.
Tygrix: 100 mg alongside six other actives.
doi.org/10.1093/eurheartj/ehr482 ↗CoQ10 · Meta-analysis
12 randomized trials
CoQ10 improved flow-mediated dilation, with larger doses giving larger effects.
Tygrix: 100 mg.
doi.org/10.1007/s40292-024-00630-8 ↗These studies tested individual ingredients, not the Tygrix formula. Individual results vary.